Filoviruses

ALL Filoviruses

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anti-Marburg GP chimeric mAb (2D8)

Anti-Marburg GP chimeric mAb (2D8) or protein A purified chimeric monoclonal antibody reactive to glycoprotein (GP) in MARV virus-like particles (VLP) and MARV recombinant glycoprotein.

Immunogen/ Target: Purified, recombinant Marburg Virus (MARV) Angola strain glycoprotein lacking the transmembrane region and the mucin domain (rGPΔmuc).
Formulation & Storage: Supplied in PBS with no preservative added. Store at +4°C for 2-3 weeks, -80°C for long term.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$586.00

anti-Marburg GP chimeric mAb (SB-04)

Anti-Marburg GP chimeric mAb (SB-04) or protein A purified human monoclonal antibody reactive to MARV-Musoke GP, MARV-Angola GP and RAVV GP. The antibody is specific to the GP2 subunit.

Immunogen/ Target: Recombinant purified Ravn Virus (RAVV) glycoprotein and recombinant Vesicular Stomatitis Virus pseudotyped expressing Marburg Virus (MARV)-Musoke glycoprotein (GP)
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$586.00

Anti-Marburg GP Macaque-derived chimeric mAb (N-125)

Anti-Marburg GP Macaque-derived chimeric mAb (N-125) is a Protein A purified, chimeric monoclonal antibody reactive to glycoproteins of Marburg virus Angola (AMARV) and Musoke (MMARV) strains. The chimeric is composed of a macaque variable region and human IgG1 Fc.

Immunogen/ Target: Filovirus recombinant glycoproteins and virus-like particles.
Formulation & Storage: Supplied in citrate-containing buffer (pH 5.5). Store at -80°C long term. Recommended to dispense into single-use aliquots.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$683.00

Ebola virus Delta Peptide

Ebola virus Delta Peptide is supplied as purified protein.

Ebola virus Delta Peptide is produced in the Ebola Zaire strain as a recombinant protein.
Purified by column chromatography

Formulation & Storage: Supplied in PBS. Store at -20°C for 2-3 weeks, -80°C for long-term.

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: N/A

Ebola virus Delta Peptide is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$600.00

Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1)

Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1) A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) that are available for your initial testing from the Sudan Ebola strain (Genebank: YP_138523.1). These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Size:

1X concentrated 25 x 200 µL ~100 wells/96 well plate

Reporter: Available with Firefly luciferase, GFP, or RFP Formulation & Storage: Available upon request. Store at -80°C. Applications

Rapid NiV pseudovirus transduction of target cells for viral entry and functional studies
Anti-NiV drug screening
Anti-NiV neutralizing antibody screening

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$4,305.00

Ebola Virus like particles (HA-EBOV) Zaire (Genebank: KJ660346.2)

Ebola Virus like particles (HA-EBOV) Zaire (Genebank: KJ660346.2) A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) from the Zaire strain that are available for your initial testing. These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Size:

1X concentrated 25 x 200 µL ~100 wells/96 well plate

Reporter: Available with Firefly luciferase, GFP, or RFP Formulation & Storage: Available upon request. Store at -80°C. Applications

Rapid NiV pseudovirus transduction of target cells for viral entry and functional studies
Anti-NiV drug screening
Anti-NiV neutralizing antibody screening

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$4,100.00

Ebola virus-like particles (EBOV VLP) (Zaire)

Virus-like Particles (VLP’s) expressing recombinant Ebola virus (EBOV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). These VLP’s mimic Ebola virus but do not contain genetic material, thus are not infectious and make an ideal candidate as a vaccine and tool to enhance filovirus research.

Formulation & Storage: Supplied in PBS (supplemented with arginine and glutamic acid). Store at 2-3 weeks at -20°C, -80°C long term. Subaliquoting is recommended to avoid repeated freeze/thaw cycles.
Pathogen Strain: Zaire
Purification: Column chromatography
Expression: SF9 cells
Please note: After thawing, VLP’s tend to sediment to bottom of the tube and appear as aggregate pellet. Resuspend by gentle vortexing or pipetting up and down
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Please email products@integratedbiotherapeutics.com for lot specific information for ‘Titer’ and ‘Usage’.

Price:

$723.00

HA Tag – Recombinant Sudan Ebola Virus GPΔTM (Mammalian)

Mature, recombinant, Sudan Virus Glycoprotein minus the transmembrane domain (SUDV rGPΔTM) is supplied as purified protein.

HA-tagged
SUDV rGPΔTM is produced in mammalian cells (HEK-293T)
Purified by FPLC

Formulation & Storage: Supplied in PBS. Store at -20°C for 2-3 weeks, -80°C for long-term.

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution

Sudan Ebola Virus GPΔTM is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$723.00

HIS Tag – Recombinant Sudan Ebola Virus GPΔTM (Mammalian)

Mature, recombinant, HIS-tagged Sudan virus Glycoprotein minus the transmembrane domain (SUDV rGPΔTM) is supplied as purified protein.

His-tagged
SUDV rGPΔTM is produced in mammalian cells
Purified by FPLC

Formulation & Storage: Supplied in PBS as liquid solution. Store at -20°C for 2-3 weeks, -80°C for long term

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution

SUDV rGPΔTM is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$723.00

Human anti-Ebola Virus GP mAb (KZ52)

Human anti-Ebola Virus GP mAb (KZ52) or protein A purified neutralizing human monoclonal antibody reactive to EBOV GP (Parren et al). The antibody detects recombinant EBOV GP without the transmembrane region (EBOV rGPΔTM) expressed in both mammalian and insect cells.

Immunogen/ Target: The human antibody KZ52 was derived from a human convalescent patient who survived an Ebola virus (EBOV) infection. KZ52 is directed towards the EBOV glycoprotein (GP).
Formulation & Storage: Supplied in buffer containing Histidine, sodium chloride and sucrose with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$621.00

Marburg virus like particles (HA-MARV) MARV001 Isolate (Genebank: OL702894.1)

Marburg virus like particles (HA-MARV) MARV001 Isolate (Genebank: OL702894.1) A novel rapid hybrid alpha-pseudovirus for Marburg (MARV) (HA-MARV) MARV001 Isolate that is available for your initial testing. These pseudoviruses are BSL-2 safe and ready to use for studying viral entry. HA-MARV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entryinhibiting drugs. Size:

1X concentrated 25 x 200 µL ~100 wells/96 well plate

Reporter: Available with Firefly luciferase, GFP, or RFP Formulation & Storage: Available upon request. Store at -80°C. Applications

Marburg pseudovirus transduction of target cells for viral entry and functional studies
Rapid Anti-Marburg drug screening
Rapid Anti-Marburg neutralizing antibody

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$6,305.00

Marburg-Musoke virus-like particles (MMARV VLP)

Virus-like Particles (VLP’s) expressing recombinant Marburg (MARV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). Since these VLP’s mimic MARV (Musoke) virus but do not contain genetic material, thus are not infectious making an ideal candidate as a vaccine and a tool to enhance filovirus research.

Formulation & Storage: Supplied in PBS (supplemented with arginine and glutamic acid). Store at 2-3 weeks at -20°C, -80°C long term. Subaliquoting is recommended to avoid repeated freeze/thaw cycles.
Pathogen Strain: Musoke
Purification: Column chromatography
Expression: SF9 cells
Please note: After thawing, VLP’s tend to sediment to the bottom of the tube and appear as aggregate pellet. VLP’s can be resuspended by gentle vortexing or by pipetting up and down, before use. Also, subaliquoting is recommended to avoid repeated freeze/thaw cycles.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$723.00

Mouse anti- Musoke Marburg virus VP40 mAb (1D1)

Mouse anti- Musoke Marburg virus VP40 mAb (1D1) or Protein A purified mouse monoclonal antibody reactive to MMARV VP40 (1D1). The antibody detects VP40 in virus-like particles (VLP) and recombinant MMARV VP40 (rMMVP40).

Immunogen/ Target: Purified recombinant Musoke Marburg virus VP40 (MMARV VP40) produced in E. coli.
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$586.00

Mouse anti-Ebola Virus GP mAb (13C6)

Mouse anti-Ebola Virus GP mAb (13C6) or protein A purified mouse monoclonal antibody reactive to EBOV GP.

Immunogen/ Target: Venezuelan equine encephalitis virus replicons encoding Ebola Virus (EBOV) glycoprotein (GP) were used to generate the original mouse monoclonal antibody.
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$621.00

Mouse anti-Ebola Virus GP mAb (4F3)

Mouse anti-Ebola Virus GP mAb (4F3) or protein G purified mouse monoclonal antibody reactive to EBOV glycoprotein (GP). The antibody detects glycoprotein in virus like particles (VLP) and EBOV glycoprotein without the transmembrane region (rGPΔTM).

Immunogen/ Target: Purified recombinant Ebola Virus (EBOV) glycoprotein lacking the transmembrane region.
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$621.00

Mouse anti-Ebola Virus VP40 mAb (3G5)

Mouse anti-Ebola Virus VP40 mAb (3G5) or Protein G purified mouse monoclonal antibody reactive to EBOV VP40. The antibody detects VP40 in virus-like particles (VLP) and recombinant protein.

Immunogen/ Target: Purified recombinant Ebola virus VP40 (EBOV rVP40) produced in E. coli.
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

IBT (0201-018) can be used as an alternative, please follow link for additional information or contact us at products@

Price:

$621.00

Mouse anti-Ebola Virus VP40 mAb (5B12)

Mouse anti-Ebola Virus VP40 mAb (5B12) or Protein G purified mouse monoclonal antibody reactive to EBOV VP40. The antibody detects VP40 in virus-like particles (VLP) and recombinant protein.

Immunogen/ Target: Purified recombinant Ebola virus VP40 (EBOV rVP40) produced in E. coli.
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$621.00

Mouse anti-Ebola Virus VP40 mAb (AE11)

Mouse anti-Ebola Virus VP40 mAb (AE11) or Purified mouse monoclonal antibody reactive to Ebola virus (EBOV) matrix protein (VP40). The antibody detects EBOV VP40 in virus-like particles (VLP) and EBOV recombinant VP40 (rVP40).

Immunogen/ Target: Purified recombinant Ebola virus VP40 (EBOV rVP40) produced in E. coli.
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications