Chikungunya Animal Models for Efficacy Testing

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus endemic in Africa and Asia that causes a debilitating disease in over 2 million people every year in explosive outbreaks.

Currently there are no vaccines or therapeutics available for this emerging virus. IBT Bioservices has established a lethal model for this disease based on previous publications
(Partidos, et al., 2011). This model utilizes AG129 mice deficient in IFN/and IFN signaling and an attenuated strain of CHIKV (181/25).

KEY FEATURES

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