| Animal Background: | Challenge Route: | Challenge Dose: | Mean Time to Death: |
|---|---|---|---|
BALB/C, C57BL/6 |
Intranasal Instillation (IN) |
Strain Dependent |
Strain and Route Dependent |
| Standard Readouts: | Other Readouts: | ||
Weights, health and survival |
Bacterial Assays (MIC), ELISA, Luminex, Flow cytometry, Survival, Temperature (via microchip), bacterial load in organs, Tissue pathology, etc. |
Description: Female BALB/c mice were challenged with S. pneumonia via the intranasal instillation (IN). Mice were treated with either saline as control or two different
test articles.
