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Rodent Breeding

Breeding colonies play a vital role in advancing scientific knowledge, preserving biodiversity, and supporting conservation efforts. Environmental stressors, changes in diet, and inbreeding can lead to genetic drift, directly affecting the immune systems and hindering therapeutic advancement.
IBT’s experienced breeders and monitored facility help limit this risk.

KEY FEATURES

Readily Available Backgrounds: Animal Background Experience: Colony: Housing:

AG129 (IFN-α/β and IFN-γ receptor double-knockout mice)

BALB/C, Various Transgenic Mice Strains

Maintain up to 50 established monogamous breeding pairs

Double filtered individually ventilated caging
Feed: Maintenance:

Irradiated 18% protein pellets, various based on strain and model

Extensive environmental monitoring, routine genetic testing, once a week handling

A balanced gender distribution among the
AG129 colony at IBT facilitates robust and
balanced studies. This data represents a
total of eight liters.

Correlation between AG129 weanling yield
and the number of monogamous breeders

The typical weight range of AG129 mice against
age in weeks from a total of 20 mice, both males
and females, per age range.

Commonly Used Models

  • Dengue and Zika Virus
  • VSV-pseudovirus Filovirus
  • Chikungunya Virus
  • Picornavirus

AG129 Features

  • Males & Females
  • Males & Females
  • Males & Females
  • Neonates

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