Sudan Virus

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Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1)

Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1) A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) that are available for your initial testing from the Sudan Ebola strain (Genebank: YP_138523.1). These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Size:

1X concentrated 25 x 200 µL ~100 wells/96 well plate

Reporter: Available with Firefly luciferase, GFP, or RFP Formulation & Storage: Available upon request. Store at -80°C. Applications

Rapid NiV pseudovirus transduction of target cells for viral entry and functional studies
Anti-NiV drug screening
Anti-NiV neutralizing antibody screening

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$4,100.00

Mouse anti-Sudan Virus GP mAb (16F6)

Mouse anti-Sudan Virus GP mAb (16F6) or purified mouse monoclonal antibody 16F6 that binds to a conformation epitope on Sudan virus (SUDV) glycoprotein (GP). This antibody demonstrates protection against SUDV both in vitro and in vivo (Dias et al., 2011 Nov 20, Nat Struct Mol Biol. 18 (12): 1424-1427).

Immunogen/ Target: Venezuelan equine encephalitis virus replicons encoding SUDV GP and gamma-radiation-inactivated SUDV-Boniface were used to generate the original mouse monoclonal antibody
Formulation & Storage: Supplied in PBS in frozen format with no preservatives added. Store at +4°C for 2-3 weeks; -80°C for long-term
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$558.00

Rabbit anti-Sudan Virus GP pAb

Rabbit anti-Sudan Virus GP pAb or protein A purified rabbit polyclonal antibody reactive to SUDV GP. The antibody detects recombinant SUDV GP (modified) and GP expressed in virus-like particles (VLP) in Western blot and ELISA.

Immunogen/ Target: Purified recombinant Sudan Ebola virus (SUDV) Glycoprotein (GP), modified.
Formulation & Storage: Supplied in PBS and 0.01% Sodium azide. Store at +4°C for 2-3 weeks, -20°C for long term.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$591.00

Rabbit anti-Sudan Virus NP pAb

Rabbit anti-Sudan Virus NP pAb or affinity purified rabbit polyclonal antibody reactive to SUDV NP. The antibody detects NP in virus-like particles (VLP) in Western blot and ELISA.

Immunogen/ Target: Peptide sequence specific to Sudan Ebola virus (SUDV) Nucleocapsid Protein (NP).
Formulation & Storage: Supplied in PBS 0.02% Sodium azide. Store at +4°C for 2-3 weeks, -20°C for long term.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$591.00

Rabbit anti-Sudan Virus sGP pAb

Rabbit anti-Sudan Virus sGP pAb or affinity purified rabbit polyclonal antibody reactive to SUDV sGP. The antibody detects sGP in Western Blot and ELISA.

Immunogen/ Target: Peptide sequence to Sudan Virus (SUDV) soluble glycoprotein (sGP).
Formulation & Storage: Supplied in PBS and 0.02% sodium azide. Store at +4°C for 2-3 weeks, -20°C for long term.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$558.00

Rabbit anti-Sudan Virus VP40 pAb

Rabbit anti-Sudan Virus VP40 pAb or affinity purified rabbit polyclonal antibody reactive to SUDV VP40. The antibody detects VP40 in virus-like particles (VLP) and recombinant SUDV VP40 (SEBOV rVP40).

Immunogen/ Target: Peptide sequence specific to Sudan Ebola virus (SUDV) VP40 matrix protein.
Formulation & Storage: Supplied in PBS 0.02% Sodium azide. Store at +4°C for 2-3 weeks, -20°C for long term.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
This antibody is intended for research use only, not for human, therapeutic, or diagnostic applications

Price:

$591.00

Recombinant Gulu Sudan Ebola virus GPΔTM

Mature, Recombinant, Gulu Sudan Ebola virus Glycoprotein minus the transmembrane domain (SUDV rGPΔTM). is supplied as purified protein.

His-tagged
SUDV rGPΔTM is produced in mammalian cells
Purified by FPLC

Formulation & Storage: Supplied in PBS. Store at -20°C for 2-3 weeks, -80°C for long term

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution

SUDV rGPΔTM is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$604.00

Recombinant Sudan Ebola virus (GPΔmuc) (Sf9)

Recombinant Protein: Sudan Ebola virus (GPΔmuc) (Sf9), or Sudan Ebola virus Glycoprotein minus the transmembrane and mucin-like domain (SUDV rGPΔmuc), His-tagged, is supplied as purified protein.

His-tagged
SUDV rGPΔmuc is produced in Sf9 insect cells using baculovirus for expression.
Purified by FPLC

Formulation & Storage: Supplied in PBS and supplemented with glycerol, arginine and glutamic acid. Store at -20°C for 2-3 weeks, -80°C for long-term.

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution

SUDV rGPΔmuc is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$571.00

Recombinant Sudan Virus Soluble GP (sGP)

Mature, Recombinant Sudan Ebolavirus Soluble Glycoprotein (SUDV sGP) is supplied as purified protein.

C-terminal His-tagged
SUDV sGP is produced in mammalian cells.
Purified by FPLC

Formulation & Storage: Supplied in PBS and supplemented with glycerol, arginine and glutamic acid. Store at -20°C for 2-3 weeks, -80°C for long term

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution

SUDV sGP is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$689.00

Recombinant Sudan Virus VP40 (SUDV VP40)

Purified, Recombinant Sudan virus VP40 (SUDV VP40) is supplied as purified protein.

Tag-free
SUDV VP40 is produced in E. coli.
Purified by FPLC

Formulation & Storage: Supplied in HEPES buffer (pH 7.5) containing sodium chloride, 5% glycerol and 0.1% Triton-X. Store at -80°C.

Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution

SUDV VP40 is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$604.00

Sudan virus-like particles (SUDV VLP)

Sudan Virus-like particles (VLP’s) expressing recombinant Sudan virus (SUDV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). These VLP’s are produced in Sf9 insect cells through infection with a recombinant baculovirus. Since these VLP’s mimic Sudan virus but do not contain genetic material, thus are not infectious and make an ideal candidate as a vaccine and also as a tool to enhance filovirus research.

Formulation & Storage: Supplied in PBS (supplemented with arginine and glutamic acid). Store at 2-3 weeks at -20°C, -80°C long term
Pathogen Strain: Boniface
Purification: Column chromatography
Expression: SF9 cells
Please note: After thawing, VLP’s tend to sediment to the bottom of the tube and appear as aggregate pellet. VLP’s can be resuspended by gentle vortexing or by pipetting up and down, before use. Also, subaliquoting is recommended to avoid repeated freeze/thaw cycles
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.