Sudan Virus

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Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1): A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) that are available for your initial testing from the Sudan Ebola strain (Genebank: YP_138523.1) These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs.   Formulation & Storage:  Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP This Ebola Virus like particles is intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$3,700.00

HIV Virus like particle (VLP’s) expressing recombinant structural proteins Safe for use in BSL-2 facilities. Formulation & Storage: Store at  -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP   Intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$3,700.00

Middle Eastern Respiratory Syndrome Corona Virus 2 (MERS-CoV-2) Virus Like Particle, Wild Type: hybrid alpha-pseudovirus for MERS-CoV-2 (Ha-MERS-CoV-2) for Wild Type strain.   The hybrid alpha-pseudovirus for MERS-CoV-2 (Ha-MERSCoV-2) is a newly developed MARS-CoV-2 virus-like particle (VLP) that encapsulates an alphavirus-derived RNA genome for rapid report expression (luciferase or GFP) in target cells (Hetrick et al., 2022). Different from commonly used S protein pseudotyped lenti- or vesicular stomatitis virus (VSV)pseudoviruses, Ha-MERS-CoV-2 is assembled with all 4 structural proteins (S, M, N, and E) of MERS-CoV-2, and contains a reporter genome derived from an alphavirusbased vector for rapid (6 hours) and robust expression of reporter genes. The alphavirus vector does not contain any of the structural proteins from the authentic virus and the alpha-pseudovirus particles are single-cycle.
  • Formulation & Storage: Store at -80°C.
  • Notes & Usage Guidelines:
  • Size:
  • •60X concentrated 5 x 100 µL
  • •1x Conc. 25 x 200uL (~100 wells)
  • Reporter: Available with Firefly luciferase, GFP, or RFP
Applications: • Screening and quantification of anti-coronavirusneutralizing antibodies • Anti-coronavirus drug screening • Quantification of viral mutants’ infectivity • Identification of host co-factors and restriction factors of coronaviruses   Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$1,490.00$2,350.00

Mouse anti-Sudan Virus GP mAb (16F6) or purified mouse monoclonal antibody 16F6 that binds to a conformation epitope on Sudan virus (SUDV) glycoprotein (GP). This antibody demonstrates protection against SUDV both in vitro and in vivo (Dias et al., 2011 Nov 20, Nat Struct Mol Biol. 18 (12): 1424-1427).
  • Immunogen/ Target Pathogen: Venezuelan equine encephalitis virus replicons encoding SUDV GP and gamma-radiation-inactivated SUDV-Boniface were used to generate the original mouse monoclonal antibody
  • Formulation: Supplied in PBS in frozen format with no preservatives added.
  • Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
  • Clonality/Isotype: Monoclonal; IgG1
  • Host: Mouse
  • Applications:
    1. ELISA: Assay-dependent dilution
    2. Western Blot: Not recommended
  Mouse anti-Sudan Virus GP mAb (16F6); Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$531.00

Rabbit anti-Sudan Virus GP pAb or protein A purified rabbit polyclonal antibody reactive to SUDV GP. The antibody detects recombinant SUDV GP (modified) and GP expressed in virus-like particles (VLP) in Western blot and ELISA.
  • Immunogen/ Target Pathogen: Purified recombinant Sudan Ebola virus (SUDV) Glycoprotein (GP), modified.
  • Formulation: Supplied in PBS and 0.01% Sodium azide.
  • Storage: Store at +4°C for 2-3 weeks, -20°C for long term.
  • Clonality/Isotype: Polyclonal; N/A
  • Host: Rabbit
  • Application:
    1. ELISA: Assay-dependent dilution
    2. Western Blot: Assay-dependent dilution
Intended for research use only, not for human, therapeutic, or diagnostic applications.  

Price:

$563.00

Rabbit anti-Sudan Virus NP pAb or affinity purified rabbit polyclonal antibody reactive to SUDV NP. The antibody detects NP in virus-like particles (VLP) in Western blot and ELISA.
  • Immunogen/ Target Pathogen: Peptide sequence specific to Sudan Ebola virus (SUDV) Nucleocapsid Protein (NP).
  • Formulation: Supplied in PBS 0.02% Sodium azide.
  • Storage: Store at +4°C for 2-3 weeks, -20°C for long term.
  • Clonality/Isotype: Polyclonal; N/A
  • Host: Rabbit
  • Applications:
    1. ELISA: Assay-dependent dilution
    2. Western Blot: Assay-dependent dilution
Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Rabbit anti-Sudan Virus sGP pAb or affinity purified rabbit polyclonal antibody reactive to SUDV sGP. The antibody detects sGP in Western Blot and ELISA.
  • Immunogen/ Target Pathogen: Peptide sequence to Sudan Virus (SUDV) soluble glycoprotein (sGP).
  • Formulation: Supplied in PBS and 0.02% sodium azide.
  • Storage: Store at +4°C for 2-3 weeks, -20°C for long term.
  • Clonality/Isotype: Polyclonal; N/A
  • Host: Rabbit
  • Applications:
    1. ELISA: Assay-dependent dilution
    2. Western Blot: Assay-dependent dilution
Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$531.00

Rabbit anti-Sudan Virus VP40 pAb or affinity purified rabbit polyclonal antibody reactive to SUDV VP40. The antibody detects VP40 in virus-like particles (VLP) and recombinant SUDV VP40 (SEBOV rVP40).
  • Immunogen/ Target Pathogen: Peptide sequence specific to Sudan Ebola virus (SUDV) VP40 matrix protein.
  • Formulation: Supplied in PBS and 0.02% Sodium azide.
  • Storage: Store at +4°C for 2-3 weeks, -20°C for long term.
  • Clonality/Isotype: Polyclonal; N/A
  • Host: Rabbit
  • Applications:
    1. ELISA: Assay-dependent dilution
    2. Western Blot: Assay-dependent dilution
Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Mature, Recombinant, Gulu Sudan Ebola virus Glycoprotein minus the transmembrane domain (SUDV rGPΔTM).
  • Contains His-tag
  • Supplied as purified protein
  • Sudan Ebola Virus Strain: Gulu
  • Produced in mammalian cells
  • Purified by FPLC
Formulation & Storage: Supplied in PBS. Store at -20°C for 2-3 weeks, -80°C for long term Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution Please Note: SUDV rGPΔTM is intended for research use only and not for human, therapeutic, or diagnostic applications.  

Price:

$575.00

Recombinant Protein: Sudan Ebola virus (GPΔmuc) (Sf9) or Sudan Ebola virus Glycoprotein minus the transmembrane and mucin-like domain (SUDV rGPΔmuc), His-tagged.
  • Produced in Sf9 insect cells using baculovirus for expression.
  • Sudan Virus recombinant protein, purified by FPLC.
  • Formulation & Storage: Supplied in PBS and supplemented with glycerol, arginine and glutamic acid. Store at -20°C for 2-3 weeks, -80°C for long-term.
  • Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.
  • This recombinant protein is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$544.00

Mature, Recombinant Sudan Ebolavirus Soluble Glycoprotein (SUDV sGP)
  • Contains a C-terminal His-tag
  • Supplied as purified protein
  • Produced in mammalian cells
  • Purified by FPLC
 
  • Formulation & Storage: Supplied in PBS and supplemented with glycerol, arginine and glutamic acid. Store at -20°C for 2-3 weeks, -80°C for long term
  • Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution
Sudan Virus Soluble Glycoprotein is intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$656.00

Purified, Recombinant Sudan virus VP40 (SUDV VP40):
  • Expressed in E. coli
  • Tag-free
  • purified using FPLC
 
  • Formulation & Storage: Supplied in HEPES buffer (pH 7.5) containing sodium chloride, 5% glycerol and 0.1% Triton-X. Store at -80°C.
  • Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: Assay-dependent dilution
Intended for research use only, not for human, therapeutic, or diagnostic applications Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$575.00

Sudan Virus-like particles (VLP’s) expressing recombinant Sudan virus (SUDV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). These VLP’s are produced in Sf9 insect cells through infection with a recombinant baculovirus. Relevance: Since these VLP’s mimic Sudan virus but do not contain genetic material, thus are not infectious and make an ideal candidate as a vaccine and also as a tool to enhance filovirus research. Formulation & Storage: Supplied in PBS (supplemented with arginine and glutamic acid). Store at 2-3 weeks at -20°C, -80°C long term Notes & Usage Guidelines: Please note: After thawing, VLP’s tend to sediment to the bottom of the tube and appear as aggregate pellet. VLP’s can be resuspended by gentle vortexing or by pipetting up and down, before use. Also, subaliquoting is recommended to avoid repeated freeze/thaw cycles

Price:

$656.00

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