Ebola

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Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1)

Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1): A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) that are available for your initial testing from the Sudan Ebola strain (Genebank: YP_138523.1) These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Formulation & Storage: Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP This Ebola Virus like particles is intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$3,700.00

Ebola Virus like particles (HA-EBOV) Zaire (Genebank: KJ660346.2)

Ebola Virus like particles (HA-EBOV) Zaire (Genebank: KJ660346.2): A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) from the Zaire strain that are available for your initial testing. These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Formulation & Storage: Available upon request Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP Virus-like particles (VLP’s) expressing recombinant GP (Glycoprotein), N (Nucleoporin), and PV40 matrix protein structural proteins This Ebola Virus like particles is intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of the datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$3,700.00

Ebola virus Soluble GP (sGP) ELISA Kit

Quantitative measurement of EBOV soluble glycoprotein in mouse and non-human primate sera

Price:

$656.25

Ebola virus-like particles (EBOV VLP) (Zaire)

Virus-like Particles (VLP’s) expressing recombinant Ebola virus (EBOV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). Are produced in Sf9 insect cells through infection with a recombinant baculovirus. Relevance: These VLP’s mimic Ebola virus but do not contain genetic material, thus are not infectious and make an ideal candidate as a vaccine and tool to enhance filovirus research.

Pathogen Strain: Zaire
Purification: Column chromatography
Expression: SF9 cells
Formulation: Supplied in PBS (supplemented with arginine and glutamic acid)
Store at 2-3 weeks at -20°C, -80°C long term. Subaliquoting is recommended to avoid repeated freeze/thaw cycles.
Please note: After thawing, VLP’s tend to sediment to bottom of the tube and appear as aggregate pellet. Resuspend by gentle vortexing or pipetting up and down.

Price:

$656.00

HIV Virus like particle (Human Immunodeficiency Virus)

HIV Virus like particle (VLP’s) expressing recombinant structural proteins Safe for use in BSL-2 facilities. Formulation & Storage: Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP Intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$3,700.00

Middle Eastern Respiratory Syndrome Corona Virus 2 (MERS-CoV-2) Virus Like Particle, Wild Type

Middle Eastern Respiratory Syndrome Corona Virus 2 (MERS-CoV-2) Virus Like Particle, Wild Type: hybrid alpha-pseudovirus for MERS-CoV-2 (Ha-MERS-CoV-2) for Wild Type strain. The hybrid alpha-pseudovirus for MERS-CoV-2 (Ha-MERSCoV-2) is a newly developed MARS-CoV-2 virus-like particle (VLP) that encapsulates an alphavirus-derived RNA genome for rapid report expression (luciferase or GFP) in target cells (Hetrick et al., 2022). Different from commonly used S protein pseudotyped lenti- or vesicular stomatitis virus (VSV)pseudoviruses, Ha-MERS-CoV-2 is assembled with all 4 structural proteins (S, M, N, and E) of MERS-CoV-2, and contains a reporter genome derived from an alphavirusbased vector for rapid (6 hours) and robust expression of reporter genes. The alphavirus vector does not contain any of the structural proteins from the authentic virus and the alpha-pseudovirus particles are single-cycle.

Formulation & Storage: Store at -80°C.
Notes & Usage Guidelines:
Size:
•60X concentrated 5 x 100 µL
•1x Conc. 25 x 200uL (~100 wells)
Reporter: Available with Firefly luciferase, GFP, or RFP

Applications: • Screening and quantification of anti-coronavirusneutralizing antibodies • Anti-coronavirus drug screening • Quantification of viral mutants’ infectivity • Identification of host co-factors and restriction factors of coronaviruses Intended for research use only, not for human, therapeutic, or diagnostic applications.