Filoviruses

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anti-Marburg GP chimeric mAb (2D8)

Anti-Marburg GP chimeric mAb (2D8) or protein A purified chimeric monoclonal antibody reactive to glycoprotein (GP) in MARV virus-like particles (VLP) and MARV recombinant glycoprotein.

Immunogen/ Target Pathogen: Purified, recombinant Marburg Virus (MARV) Angola strain glycoprotein lacking the transmembrane region and the mucin domain (rGPΔmuc).
Formulation: Supplied in PBS with no preservative added.
Storage: Store at +4°C for 2-3 weeks, -80°C for long term.
Clonality/Isotype: Monoclonal; IgG1
Host: Chimeric
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$631.00

anti-Marburg GP chimeric mAb (SB-04)

Anti-Marburg GP chimeric mAb (SB-04) or protein A purified human monoclonal antibody reactive to MARV-Musoke GP, MARV-Angola GP and RAVV GP. The antibody is specific to the GP2 subunit.

Immunogen/ Target Pathogen: Recombinant purified Ravn Virus (RAVV) glycoprotein and recombinant Vesicular Stomatitis Virus pseudotyped expressing Marburg Virus (MARV)-Musoke glycoprotein (GP)
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG1
Host: Human
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$531.00

Anti-Marburg GP Macaque-derived chimeric mAb (R80)

Anti-MARV GP Macaque-derived chimeric mAb (R80); Protein A purified, chimeric monoclonal antibody reactive to glycoproteins of Marburg virus Angola (AMARV) and Musoke (MMARV) strains.

Immunogen/ Target Pathogen: Filovirus recombinant glycoproteins and virus-like particles.
Formulation: Supplied in citrate-containing buffer (pH 5.5).
Storage: Store at -80°C long term. Recommended to dispense into single-use aliquots.
Clonality/Isotype: Monoclonal; N/A
Host: Macaque
Applications
1. ELISA: Assay-dependent dilution
2. Western Blot: NA
Purification: Protein A purified
Pathogen Strain: Angola, Musoke

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$619.00

Ebola virus Delta Peptide

Recombinant Protein: Ebola virus delta peptide

Expressed and harvested from the Ebola Zaire strain as a recombinant protein.
Purified by Column Chromatography.
Formulation & Storage: Supplied in PBS. Store at -20°C for 2-3 weeks, -80°C for long-term.
Notes & Usage Guidelines: ELISA: Assay-dependent dilution WB: N/A
This product is intended for research use only, not for human, therapeutic, or diagnostic applications.
Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$544.00

Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1)

Ebola Virus like particles (HA-EBOV) Sudan (Genebank: YP_138523.1): A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) that are available for your initial testing from the Sudan Ebola strain (Genebank: YP_138523.1) These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Formulation & Storage: Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP This Ebola Virus like particles is intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$4,100.00

Ebola Virus like particles (HA-EBOV) Zaire (Genebank: KJ660346.2)

Ebola Virus like particles (HA-EBOV) Zaire (Genebank: KJ660346.2): A novel rapid hybrid alpha-pseudovirus for Ebolaviruses (EBOV) (HA-EBOV) from the Zaire strain that are available for your initial testing. These pseudoviruses are BSL2 safe and ready to use for studying viral entry. HAEBOV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entry-inhibiting drugs. Formulation & Storage: Available upon request Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP Virus-like particles (VLP’s) expressing recombinant GP (Glycoprotein), N (Nucleoporin), and PV40 matrix protein structural proteins This Ebola Virus like particles is intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of the datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$4,100.00

Ebola virus-like particles (EBOV VLP) (Zaire)

Virus-like Particles (VLP’s) expressing recombinant Ebola virus (EBOV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40). Are produced in Sf9 insect cells through infection with a recombinant baculovirus. Relevance: These VLP’s mimic Ebola virus but do not contain genetic material, thus are not infectious and make an ideal candidate as a vaccine and tool to enhance filovirus research.

Pathogen Strain: Zaire
Purification: Column chromatography
Expression: SF9 cells
Formulation: Supplied in PBS (supplemented with arginine and glutamic acid)
Store at 2-3 weeks at -20°C, -80°C long term. Subaliquoting is recommended to avoid repeated freeze/thaw cycles.
Please note: After thawing, VLP’s tend to sediment to bottom of the tube and appear as aggregate pellet. Resuspend by gentle vortexing or pipetting up and down.

Price:

$656.00

Human anti-Ebola Virus GP mAb (KZ52)

Human anti-Ebola Virus GP mAb (KZ52) or protein A purified neutralizing human monoclonal antibody reactive to EBOV GP (Parren et al). The antibody detects recombinant EBOV GP without the transmembrane region (EBOV rGPΔTM) expressed in both mammalian and insect cells.

Immunogen/ Target Pathogen: The human antibody KZ52 was derived from a human convalescent patient who survived an Ebola virus (EBOV) infection. KZ52 is directed towards the EBOV glycoprotein (GP).
Formulation: Supplied in buffer containing Histidine, sodium chloride and sucrose with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG1
Host: Human
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Marburg virus like particles (HA-MARV) MARV001 Isolate (Genebank: OL702894.1)

Marburg virus like particles (HA-MARV) MARV001 Isolate (Genebank: OL702894.1) : A novel rapid hybrid alpha-pseudovirus for Marburg (MARV) (HA-MARV) MARV001 Isolate that is available for your initial testing. These pseudoviruses are BSL-2 safe and ready to use for studying viral entry. HA-MARV particles are pseudoviruses assembled from the structural proteins of the filovirus glycoprotein (GP), VP40 matrix protein, and the Nucleoprotein (NP) and package an alphaviral vector for reporter gene expression. The alpha-pseudoviruses are single-cycle viruses with self-replicating RNA for rapid quantification of neutralizing antibodies and entryinhibiting drugs. Formulation & Storage: Available upon request Store at -80°C. Notes & Usage Guidelines: Size: 1X concentrated 25 x 200 µL ~100 wells/96 well plate Reporter: Available with Firefly luciferase, GFP, or RFP Applications:

Marburg pseudovirus transduction of target cells for viral entry and functional studies
Rapid Anti-Marburg drug screening
Rapid Anti-Marburg neutralizing antibody

This Marburg virus like particles is Intended for research use only, not for human, therapeutic, or diagnostic applications. Certificate of analysis: A hardcopy of datasheet is sent along with the products. Please refer to it for detailed information.

Price:

$4,100.00

Marburg-Musoke virus-like particles (MMARV VLP)

Virus-like Particles (VLP’s) expressing recombinant Marburg (MARV) glycoprotein (GP), nucleoprotein (NP), and matrix protein (VP40).

Marburg Strain: Musoke
These VLP’s are produced in Sf9 insect cells through infection with a recombinant baculovirus.
Relevance: Since these VLP’s mimic MARV (Musoke) virus but do not contain genetic material, thus are not infectious making an ideal candidate as a vaccine and a tool to enhance filovirus research.
Notes & Usage Guidelines: Please note: After thawing, VLP’s tend to sediment to the bottom of the tube and appear as aggregate pellet. VLP’s can be resuspended by gentle vortexing or by pipetting up and down, before use. Also, subaliquoting is recommended to avoid repeated freeze/thaw cycles.

Price:

$656.00

Mouse anti- Musoke Marburg virus VP40 mAb (1D1)

Mouse anti- Musoke Marburg virus VP40 mAb (1D1) or Protein A purified mouse monoclonal antibody reactive to MMARV VP40 (1D1). The antibody detects VP40 in virus-like particles (VLP) and recombinant MMARV VP40 (rMMVP40).

Immunogen/ Target Pathogen: Purified recombinant Musoke Marburg virus VP40 (MMARV VP40) produced in E. coli.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG1
Host: Mouse
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$531.00

Mouse anti-Ebola Virus GP mAb (13C6)

Mouse anti-Ebola Virus GP mAb (13C6) or protein A purified mouse monoclonal antibody reactive to EBOV GP.

Immunogen/ Target Pathogen: Venezuelan equine encephalitis virus replicons encoding Ebola Virus (EBOV) glycoprotein (GP) were used to generate the original mouse monoclonal antibody.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG2a
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Not recommended

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Mouse anti-Ebola Virus GP mAb (4F3)

Mouse anti-Ebola Virus GP mAb (4F3) or protein G purified mouse monoclonal antibody reactive to EBOV glycoprotein (GP). The antibody detects glycoprotein in virus like particles (VLP) and EBOV glycoprotein without the transmembrane region (rGPΔTM).

Immunogen/ Target Pathogen: Purified recombinant Ebola Virus (EBOV) glycoprotein lacking the transmembrane region.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG2
Host: Mouse
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Mouse anti-Ebola Virus VP40 mAb (3G5)

Mouse anti-Ebola Virus VP40 mAb (3G5) or Protein G purified mouse monoclonal antibody reactive to EBOV VP40. The antibody detects VP40 in virus-like particles (VLP) and recombinant protein.

Immunogen/ Target Pathogen: Purified recombinant Ebola virus VP40 (EBOV rVP40) produced in E. coli.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG1
Host: Mouse
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Mouse anti-Ebola Virus VP40 mAb (5B12)

Mouse anti-Ebola Virus VP40 mAb (5B12) or Protein G purified mouse monoclonal antibody reactive to EBOV VP40. The antibody detects VP40 in virus-like particles (VLP) and recombinant protein.

Immunogen/ Target Pathogen: Purified recombinant Ebola virus VP40 (EBOV rVP40) produced in E. coli.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG2b
Host: Mouse
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$563.00

Mouse anti-Ebola Virus VP40 mAb (AE11)

Mouse anti-Ebola Virus VP40 mAb (AE11) or Purified mouse monoclonal antibody reactive to Ebola virus (EBOV) matrix protein (VP40). The antibody detects EBOV VP40 in virus-like particles (VLP) and EBOV recombinant VP40 (rVP40).

Immunogen/ Target Pathogen: Purified recombinant Ebola virus VP40 (EBOV rVP40) produced in E. coli.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG2a
Host: Mouse
Application:
1. ELISA: Assay-dependent dilution
2. Western Blot: Not recommended

Price:

$563.00

Mouse anti-Marburg GP mAb (5C1)

Mouse anti-Marburg GP mAb (5C1) or Protein A purified mouse monoclonal antibody against MMARV GP (5C1) (detects GP in virus-like particles (VLP) and recombinant MMARV GP without the transmembrane region )

Immunogen/ Target Pathogen: Purified, recombinant Lake Victoria Marburgvirus Musoke strain (MMARV) glycoprotein lacking the transmembrane region (rGPΔTM).
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG1
Host: Mouse
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.

Price:

$531.00

Mouse anti-Musoke Marburgvirus VP40 mAb (6B1)

Mouse anti-Musoke Marburgvirus VP40 mAb (6B1) or Protein A purified mouse monoclonal antibody reactive to MMARV VP40 (6B1). The antibody detects VP40 in virus-like particles (VLP) and recombinant MMARV VP40 (rMMVP40).

Immunogen/ Target Pathogen: Purified recombinant Musoke Marburgvirus VP40 (MMARV VP40) produced in E.coli.
Formulation: Supplied in PBS in frozen format with no preservatives added.
Storage: Store at +4°C for 2-3 weeks; -80°C for long-term
Clonality/Isotype: Monoclonal; IgG2
Host: Mouse
Applications:
1. ELISA: Assay-dependent dilution
2. Western Blot: Assay-dependent dilution

Intended for research use only, not for human, therapeutic, or diagnostic applications.