Protein A purified, human monoclonal antibody reactive to Ebola virus (EBOV), Sudan virus (SUDV) and Bundibugyo virus (BDBV) glycoproteins.
Immunogen: Filovirus recombinant glycoproteins and virus-like particles.
Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescent or LC-MS detection.
Immunogen / Target: Human Multidrug Resistance Protein 8 (MRP8)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescent or LC-MS detection.
Immunogen / Target: Human Multidrug Resistance Protein 5 (MRP5)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescent or LC-MS detection.
Immunogen / Target: Human Multidrug Resistance Protein 4 (MRP4)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescent or LC-MS detection.
Immunogen / Target: Human Multidrug Resistance Protein 3 (MRP3)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Recombinant Vesicular Stomatitis Virus (rVSV) pseudotyped with Bundibugyo ebolavirus glycoprotein (rVSV-BDBV-GP) system in which the G protein of VSV has been deleted, replaced with firefly luciferase and used to produce VSV-pseudotyped virus containing the envelope glycoprotein of Bundibugyo ebolavirus virus. Since the infectivity of pseudotyped virus is restricted to a single round of replication, analyses of viral entry can be performed using just biosafety level 2 (BSL-2) containment.
Formulation & Storage: Supplied in EMEM™ (Gibco) supplemented with 1% Fetal Bovine Serum, L-glutamine and Penicillin/Streptomycin. Store at -80°C.
Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescent or LC-MS detection.
Immunogen / Target: Human Multidrug Resistance Protein 2 (MRP2)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescent or LC-MS detection.
Immunogen / Target: Human Multidrug Resistance Protein 1 (MRP1)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporter (ABC transporters) vesicles are inside-out human embryonic kidney (HEK293) membrane vesicles prepared for high-throughput, ATP-dependent transport assays with detection by radiolabel, fluorescence, or LC-MS.
Immunogen / Target:Â Breast Cancer Resistance Protein (BCRP)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporter (ABC transporter) vesicles are inside-out HEK293 membrane vesicles designed for high-throughput, ATP-dependent substrate transport assays with detection by radiolabel, fluorescence, or LC-MS.
Immunogen / Target: Multidrug Resistance 1 (MDR1)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4×500μL
Expiration date: 2 years from the date of shipping
Unit Size: 100 reactions / kit (96-wells format)
Refreeze: Snap freeze vesicles with liquid nitrogen; store at-80°C
Human drug efflux transporter vesicles are inside-out HEK293 membrane vesicles prepared for high-throughput, ATP-dependent substrate transport assays with detection by radiolabel, fluorescence, or LC-MS.
Immunogen / Target:Â Blue Salt Export Pump (BSEP)
Notes & Usage Guidelines:Protein Concentration: 1.5 mg/mL
Volume: 4 x 500uL
Unit Size: 100 reactions / kit (96-wells format)
Expiration Date: 2 years from date of shipping
Refreeze: Snap freeze vesicles with liquid nitrogen; store at -80°C
