Position Overview

IBT Bioservices is seeking an experienced, independent, and highly technical Scientist III to join our expanding immunology team. The ideal candidate will serve as a key subject matter expert in advanced flow cytometry and assay development within a fast-paced, high-volume Contract Research Organization (CRO) environment.

In this role, you will be responsible for end-to-end execution of complex immunological studies, from tissue processing to high-parameter data analysis. You must be adept at troubleshooting, panel design, and the rigorous validation of assays in compliance with project requirements.

Key Responsibilities

• Flow Cytometry Expertise:
  • Serve as the lead operator for the BD FACSymphony A2 (or equivalent).
  • Perform routine machine maintenance, calibration, quality control, and troubleshooting to ensure optimal performance.
  • Design and validate complex 17+ color panels tailored to specific research objectives.
  • Independently perform mouse tissue harvests, including spleen and lung processing.
  • Execute flow cytometry experiments for diverse sample types, including human, non-human primate (NHP), and murine models.
• Assay Development & Sample Testing:
  • Participate in development, optimization, and qualification of robust viral or immunology-based assays, ensuring full adherence to internal quality standards, GXP-guidelines, and aggressive client timelines.
  • Proactively troubleshoot assay performance issues to guarantee high data integrity and consistency in a high-volume, fast-paced environment.
  • Demonstrate exceptional pipetting precision and consistency, with the proven ability to handle high-throughput demands—specifically the capacity to execute 50+ 96-well plates per week while maintaining tight Coefficient of Variation (CV) targets.
  • Apply a deep understanding of XLFit (or similar), standard curve analysis and assay linearity to validate performance and ensure reliable quantitative results.
• Technical Support & Documentation:
  • Maintain detailed batch records and prepare technical reports summarizing findings.
  • Collaborate with cross-functional teams to align on study protocols and data interpretation.

Qualifications & Requirements

• Education: PhD in Immunology, Cell Biology, Microbiology, or a related scientific discipline.
• Experience: Minimum of 4–6 years of professional experience in a high-volume environment, CRO preferred.
• Authorization to work in US and Maryland residency
• Technical Skills:
  • Hands-on experience with high-parameter flow cytometry (specifically BD Symphony or similar platforms).
  • Demonstrated capability in advanced panel design and multi-color compensation.
  • Strong background in assay development and qualification methodologies.
  • 3+ years of experience on BD Symphony A2 or similar (13+ color).
• Preferred Skills: * Basic operational knowledge or experience with qPCR and ELISPOT techniques is a plus.
• Soft Skills:
  • Highly independent professional, with proven proficiency in maintaining meticulous, audit-ready documentation in a fast-paced, high-volume setting.
  • Ability to manage multiple concurrent projects with rigorous attention to detail.
  • Strong communication skills, capable of relaying (written and oral) technical data to internal and external stakeholders.