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Streptococcus pneumoniae Pneumonia Model

BALB/c or C57BL/6 mice are challenged intranasally with Streptococcus pneumoniae and observed for 5-15 days post infection.

Endpoints include mortality, morbidity, or CFU measurement (sub-lethal challenge) in blood, lung, spleen or other organs.

KEY FEATURES

Description: Female BALB/c mice were challenged with S. pneumonia via the intranasal instillation (IN). Mice were treated with either saline as control or two different
test articles.

S. pneumoniae Strains

  • DCC1335
  • DCC1420
  • 6b2092
  • D38 ST2

Testing Available

  • In vivo efficacy, MIC/MBC
  • In vivo efficacy, MIC/MBC
  • In vivo efficacy, MIC/MBC
  • In vivo efficacy, MIC/MBC

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