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Enzyme-Linked Immunosorbent Assay (ELISA) Testing

At IBT Bioservices, we specialize in providing comprehensive preclinical ELISA testing services to support research, drug development, and diagnostic applications. ELISA is a widely used immunoassay technique that allows for the detection and quantification of target analytes, such as proteins, antibodies, hormones, cytokines, and small molecules, with high sensitivity and specificity.

Serology ELISAs

Serology testing is essential for evaluating the potential immune responses elicited by therapeutic proteins, biologics, and vaccines. We provide ELISA-based serology assays to detect and quantify the presence of anti-drug antibodies (ADAs) in biological samples. Our immunogenicity testing helps assess the immunogenic potential of therapeutic agents, identify potential adverse reactions, and support regulatory submissions.

Assay Development

Our experienced team of scientists can design and develop customized ELISA assays tailored to your specific research objectives. We work closely with clients to optimize assay conditions, antibody selection, and sample preparation protocols to ensure robust and accurate results. Our assays undergo rigorous development to meet the highest standards of quality, precision, and reliability.

Pharmacokinetic (PK) Studies

ELISA can be utilized to determine the pharmacokinetic profiles of therapeutic agents in preclinical studies. We offer ELISA-based PK assays to measure drug concentrations in various matrices, including plasma, serum, and urine. Our PK studies provide critical data on drug absorption, distribution, metabolism, and elimination, helping to optimize dosing regimens and assess drug bioavailability.

Cytokine Profiling

ELISA-based cytokine profiling allows for the simultaneous measurement of multiple cytokines and growth factors in biological samples. We offer cytokine profiling panels tailored to specific research needs, enabling the comprehensive evaluation of immune responses, inflammation, and disease progression. Our cytokine profiling assays provide valuable insights into the complex interplay of cytokines and their roles in various physiological and pathological processes.

This assay tests for hemagglutinin (HA)-specific antibodies against influenza virus (INFV). Serial dilutions of the TA starting are incubated with a standardized amount of IFV antigen and Turkey Red Blood Cells (TRBCs) in 96-well plates. In the absence of antibodies against influenza hemagglutinin (HA) glycoprotein, the HA protein agglutinates TRBCs. Hemagglutination is inhibited in the presence of HA-specific antibodies, which will bind to the antigenic sites on the HA protein. The number of antibodies present in a sample is quantified as an HA titer, given as the highest dilution of serum that completely inhibits hemagglutination. IBT’s method is standardized to the WHO testing protocol and can use live virus for testing.

Contact us today to learn more about our preclinical ELISA testing services and how we can support your specific research and development needs.

WHY CHOOSE IBT?

EXPERTISE

Our team of scientists and technicians are highly skilled and experienced in conducting HAI assays, ensuring accurate and reliable results.

CUSTOMIZED SOLUTIONS

We understand the unique needs of each research project and provide customized assay designs to meet your specific requirements.

TIMELY RESULTS

We prioritize efficiency without compromising on quality. Our streamlined processes and advanced equipment allow for quick turnaround times, ensuring you receive results promptly.

QUALITY ASSURANCE:

We maintain rigorous quality control measures throughout our operations, ensuring the accuracy and reproducibility of our assay results.

EXCEPTIONAL SUPPORT:

Our dedicated customer support team is always available to address your queries and provide assistance at every step of the process.