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Biodistribution

At IBT Bioservices we offer comprehensive services for biodistribution studies, which play a crucial role in assessing the distribution and accumulation of drugs, nanoparticles, or other therapeutics within the body. Biodistribution studies provide valuable insights into how a substance is distributed, metabolized, and eliminated in various organs and tissues, aiding in the development and optimization of therapeutic interventions.
At IBT Bioservices, we are dedicated to providing you with reliable and comprehensive biodistribution studies. Our state-of-the-art facilities, cutting-edge technologies, and experienced scientific team make us the preferred partner for pharmaceutical companies, research institutions, and academic researchers.
Our team of experts provides comprehensive data analysis and interpretation for biodistribution studies. We utilize advanced statistical analysis tools to evaluate substance distribution patterns, calculate tissue-to-plasma ratios, and perform comparative analysis. We deliver detailed reports summarizing the findings and assisting you in making informed decisions for further development.

Key Features of Our Biodistribution Studies

Customized Study Design

Customized Study Design

We understand that each substance and therapeutic application has unique requirements, and we tailor our study designs to meet your specific needs. Our team of experienced scientists works closely with you to develop customized protocols, considering factors such as the substance’s physicochemical properties, administration route, dosage, and target tissues. We ensure that the study design aligns with your research goals and regulatory requirements.

Animal Models

Animal Models

We offer a wide range of well-established animal models for biodistribution studies, including mice, rats, and non-human primates. These models allow us to investigate the biodistribution of substances in a controlled and relevant biological system. We help you select the most appropriate animal model based on the therapeutic target, route of administration, and translatability to humans.

Tissue Sample Analysis

Tissue Sample Analysis

We perform detailed ex vivo analysis of tissues to determine the concentration of the substance of interest. We utilize various analytical methods, such as liquid chromatography-mass spectrometry (LC-MS), to accurately measure the substance’s concentration in specific organs and tissues. This analysis helps identify tissue-specific accumulation patterns and provides insights into metabolism and elimination pathways

Pharmacokinetic Analysis

Pharmacokinetic Analysis

Our team conducts pharmacokinetic analysis to assess the substance’s absorption, distribution, metabolism, and excretion (ADME) characteristics. By evaluating parameters such as maximum concentration (Cmax), time to reach Cmax (Tmax), half-life, and area under the curve (AUC), we gain insights into the substance’s systemic exposure and clearance from the body.
Contact us today to discuss your biodistribution study requirements and learn how we can support your research and development program.